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Search Results for " glucosylceramide synthase (gcs) "

9

Compounds

Cat No. Product Name Synonyms Targets
TQ0155 Miglustat hydrochloride NB-DNJ hydrochloride,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride Transferase
Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease.
T4473 Ibiglustat Venglustat,SAR402671,GZ402671 Transferase
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe...
T3663 Eliglustat GENZ-112638,Genz 99067 Transferase
Eliglustat (Genz 99067) is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease.
T62898 Glucosylceramide synthase-IN-1
Glucosylceramide synthase-IN-1 (T-036) is a potent, orally active, blood-brain barrier permeable glucosylceramide synthase (GCS) inhibitor that acts on human GCS (IC50: 31 nM) and mouse GCS (IC50: 51 nM). Glucosylceramid...
T70685 CCG-203586
CCG-203586 is a novel potent glucosylceramide synthase (GCS) inhibitor.
T61632 Glucosylceramide synthase-IN-3
Glucosylceramide synthase-IN-3 (compound BZ1) is a highly potent, brain-penetrant, and orally active inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 value of 16 nM for human GCS. This compound, designate...
T62664 Glucosylceramide synthase-IN-2
Glucosylceramide synthase-IN-2 (compound T-690) is a potent, blood-brain barrier-permeable, orally active inhibitor of glucosylceramide synthase (GCS) that acts on human GCS (IC50: 15 nM) and mouse GCS (IC50: 190 nM). Gl...
T70336 Nizubaglustat
Nizubaglustat acts as an inhibitor of Ceramide Glucosyltransferase, also known as Glucosylceramide Synthase (GCS), and additionally inhibits GBA2, which is involved in neuropathological lysosomal storage disorders.
T39105 Ibiglustat succinate GZ402671succinate,Venglustat succinate,Ibiglustat succinate,SAR402671succinate
Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant inhibitor of glucosylceramide synthase (GCS). It is utilized in the investigation of Gaucher disease type 3, Parkinson's disease associated with GBA ...
TargetMol