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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0155 | Miglustat hydrochloride | NB-DNJ hydrochloride,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride | Transferase |
Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease. | |||
T4473 | Ibiglustat | Venglustat,SAR402671,GZ402671 | Transferase |
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe... | |||
T3663 | Eliglustat | GENZ-112638,Genz 99067 | Transferase |
Eliglustat (Genz 99067) is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease. | |||
T62898 | Glucosylceramide synthase-IN-1 | ||
Glucosylceramide synthase-IN-1 (T-036) is a potent, orally active, blood-brain barrier permeable glucosylceramide synthase (GCS) inhibitor that acts on human GCS (IC50: 31 nM) and mouse GCS (IC50: 51 nM). Glucosylceramid... | |||
T70685 | CCG-203586 | ||
CCG-203586 is a novel potent glucosylceramide synthase (GCS) inhibitor. | |||
T61632 | Glucosylceramide synthase-IN-3 | ||
Glucosylceramide synthase-IN-3 (compound BZ1) is a highly potent, brain-penetrant, and orally active inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 value of 16 nM for human GCS. This compound, designate... | |||
T62664 | Glucosylceramide synthase-IN-2 | ||
Glucosylceramide synthase-IN-2 (compound T-690) is a potent, blood-brain barrier-permeable, orally active inhibitor of glucosylceramide synthase (GCS) that acts on human GCS (IC50: 15 nM) and mouse GCS (IC50: 190 nM). Gl... | |||
T70336 | Nizubaglustat | ||
Nizubaglustat acts as an inhibitor of Ceramide Glucosyltransferase, also known as Glucosylceramide Synthase (GCS), and additionally inhibits GBA2, which is involved in neuropathological lysosomal storage disorders. | |||
T39105 | Ibiglustat succinate | GZ402671succinate,Venglustat succinate,Ibiglustat succinate,SAR402671succinate | |
Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant inhibitor of glucosylceramide synthase (GCS). It is utilized in the investigation of Gaucher disease type 3, Parkinson's disease associated with GBA ... |